Lots of midweek changes for both sides as Tottenham Hotspur travel to Craven Cottage to take on a Fulham team in flux.
Rene Meulensteen makes his Premier League managerial debut, in for the sacked Martin Jol, live online at NBC Sports Live Extra at 3:00pm ET.
The Dutch manager has brought in Greek midfielder Giorgis Karagounis to energize the middle of the pitch, while Alex Kacaniklic and John Arne Riise also return to the side.
For Andre Villas-Boas, his weekend draw with Manchester United in the rear view mirror, injured Moussa Dembele fails to make the squad while Etienne Capoue replaces him in the central midfield.
Jermain Defoe also gets a rare start up front, with the struggling Roberto Soldado sent back to the substitutes.
No surprise that Tottenham are making a number of changes, considering this will be their third match in 10 days, and another one upcoming on Saturday.
Fulham: Stekelenburg; Riether, Hughes, Senderos, Riise; Karagounis, Parker; Kacaniklic, Kasami, Dejagah; Berbatov.
Bench – Stockdale, Zverotic, Boateng, Sidwell, Duff, Taarabt, Ruiz.
Tottenham Hotspur – Lloris; Walker, Chiriches, Dawson, Vertonghen; Sandro, Capoue; Lennon, Paulinho, Lamela; Defoe
Bench – Friedel, Naughton, Chadli, Holtby, Sigurdsson, Townsend, Soldado.