Southampton look to turn their fortunes around and stay in the top half of the table as they hit the road to St. James Park at 10am ET live online at NBC Sports Live Extra.
Manager Mauricio Pochettino has gone very attacking on the road, picking both strikers Rickie Lambert and Daniel Osvaldo, with Adam Lallana sacrificed to the bench.
He is missing a number of options thanks to the injury bug, with Victor Wanyama, Danny Fox, and Nathaniel Clyne are all sidelined along with goalkeeper Artur Boruc.
The match has a bit of extra meaning for Newcastle manager Alan Pardew, who was sacked way back when by Saints quite unceremoniously, and he still publicly holds some hard feelings.
The Magpies are slowly crawling up the table rather under the radar, all the way up to seventh, three clear of Saints below them. Southampton could draw level with an away win and jump Newcastle on goal difference.
A big miss for Newcastle at home will be midfielder Yohan Cabaye, absent at home due to yellow card accumulation.
Newcastle – Krul; Debuchy, Coloccini, Williamson, Santon; Sissoko, Anita, Tiote, Gouffran; Shola Ameobi, Remy.
Bench – Elliot, Yanga-Mbiwa, Haidara, Obertan, Sammy Ameobi, Ben Arfa, Cisse.
Southampton – Gazzaniga; Chambers, Lovren, Hooiveld, Shaw; Cork, S. Davis, Ward-Prowse, Rodriguez; Lambert, Osvaldo.
Bench – Cropper, Yoshida, Schneiderlin, Fonte, Ramírez, Lallana, Gallagher.