Mauricio Pochettino continues to try and find his best lineup, making three changes from last week’s win over Hull City as he welcomes Everton to White Hart Lane.
The two match up live on NBCSN at 11am ET or live online at NBC Sports Live Extra.
Moussa Dembele, Erik Lamela, and Eric Dier all sit as Pochettino looks for back-to-back wins for the first time this season since the opening two weeks.
Yet another Europa League win midweek will see them try to buck a troubling trend of weekend hangover, having lost their last three Premier League fixtures following European wins.
Everton won in the Europa League as well over the week, with both sides essentially through to the next round.
Gareth Barry and Leighton Baines have passed fitness tests to make the starting lineup for the visiting Toffees, while Steven Pienaar can only make the bench, and Steven Naismith is unable to make the roster with a hamstring injury.
Tottenham: Lloris, Vertonghen, Chiriches, Fazio, Davies, Bentaleb, Mason, Lennon, Eriksen, Kane, Soldado.
Bench: Vorm, Kaboul, Paulinho, Lamela, Dier, Dembele, Chadli.
Everton: Howard, Baines, Jagielka, Distin, Coleman, Barry, Besic, Eto’o, Barkley, Mirallas, Lukaku.
Bench: Robles, Hibbert, McGeady, Atsu, Osman, Pienaar, Garbutt.