Watch Live: Manchester United vs. Southampton (Lineups, Live Stream)

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Manchester United host Southampton at Old Trafford on Friday (Watch live, 3 p.m. ET on USA Network and online via NBC Sports) as “Friday Night Football” arrives in the Premier League.

Jose Mourinho will make his home debut as United’s manager in the PL, while Paul Pogba will also return as a United player after his world-record transfer from Juventus.

WATCH LIVE ONLINE HERE

Southampton’s new manager Claude Puel will take charge of his his first away game and it couldn’t be any tougher with a real feel-good factor sweeping through United ahead of the new season.

In team news United bring in Paul Pogba for Ander Herrera in one change from the team which beat Bournemouth.

Southampton make two changes with Jose Fonte in for Maya Yoshida and Pierre-Emile Hojbjerg for James Ward-Prowse.

LINEUPS

Manchester United: De Gea; Valencia, Blind, Bailly, Shaw; Fellaini, Carrick; Martial, Rooney, Mata; Ibrahimovic. Subs: Romero, Young, Rashford, Smalling, Herrera, Mkhitaryan, Schneiderlin

Southampton: Forster; Cedric, Fonte, Van Dijk, Targett; Romeu, Hojbjerg, Davis, Tadic; Redmond, Long. Subs: Yoshida, Clasie, Rodriguez, Austin, McCarthy, Ward-Prowse, Pied