There will be four All-Premier League match-ups when the top two tiers enter the FA Cup in early January.
The most intriguing of the bunch, should the sides go close to full-strength, is West Ham United hosting Manchester City.
Five relegation candidates also have to face Premier League opposition: Burnley goes to Sunderland, Hull City hosts Swansea, and Leicester City is off to Everton.
Alluring for Manchester United fans is the return of stalwart defender Jaap Stam to Old Trafford, as the big Dutch manager brings Reading to town.
The matches will take place between Jan. 6-9.
FA Cup third round draw
Ipswich Town vs. Lincoln/Oldham
Barrow vs. Rochdale
Manchester United vs. Reading
Hull City vs. Swansea
Sunderland vs. Burnley
QPR vs. Blackburn
Millwall vs. Bournemouth
West Ham United vs. Manchester City
Brighton vs. MK Dons/Charlton
Blackpool vs. Barnsley
Wigan Athletic vs. Nottingham Forest
Birmingham City vs. Newcastle United
Chelsea vs. Peterborough/Notts County
Middlesbrough vs. Sheff Wednesday
West Bromwich Albion vs. Derby County
Everton vs. Leicester City
Liverpool vs. Newport/Plymouth
Wycombe vs. Northampton/Stourbridge
Watford vs. Burton Albion
Preston North End vs. Arsenal
Cardiff City vs. Fulham
Stoke City vs. Wolves
Cambridge United vs. Leeds United
Bristol City vs. Shrewsbury/Fleetwood
Huddersfield vs. Port Vale
Tottenham Hotspur vs. Aston Villa
Brentford vs. Halifax/Eastleigh
Bolton vs. Crystal Palace
Norwich City vs. Southampton
Sutton United vs AFC Wimbledon
Accrington vs. Luton Town
Rotherham vs. Oxford/Macclesfield