Also omitted were Napoli’s Jose Callejoin and Arsenal’s Hector Bellerin.
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Spain is expected to contend for the tournament crown in Russia, led by a stellar midfield which includes Silva, Andres Iniesta, Isco, and Thiago Alcantara.
Spain is in a group with Portugal, Iran, and Morocco.
Spain’s World Cup squad
Goalkeepers: De Gea, Kepa Arrizabalaga, Pepe Reina
Defenders: Gerard Pique, Sergio Ramos, Azpilicueta, Nacho, Alvaro Odriozola, Jordi Alba, Monreal, Dani Carvajal
Midfielders: Sergio Busquets, Asensio, Iniesta, Isco, Saul Niguel, Thiago Alcantara, Koke, Silva.
Forwards: Diego Costa, Rodrigo, Iago Aspas, Lucas Vazquez.