Rashford scored in the 27th minute with a beautiful move down the left that threw two Leeds defenders into each other, while James struck the post just before halftime on an overlap down the right in his Red Devils debut.
Also on the scoresheet was 17-year-old Mason Greenwood who received a hard, low cross from fellow debutant Aaron Wan-Bissaka and beat two Leeds defenders in a footrace to the ball on the doorstep for a sliding finish. The move was started by Paul Pogba who found the new Manchester United defender down the right with a wonderful through-ball, leading to the delivery into the box. Greenwood has had quite the last 12 months, scoring for the Manchester United U-17, U-18, U-23, and now senior side all in that span.
After the break, Phil Jones found the back of the net by powering home a corner with his head, while Anthony Martial finished off the scoreline with a penalty after Tahith Chong was fouled in the area by Liam Cooper. Chong impressed throughout the second half, linking well with fellow Manchester United youth product Angel Gomes.
Ole Gunnar Solskjaer found playing time for just about every first-teamer, completely changing the side at halftime. Nemanja Matic was one of the halftime introductions, but was curiously withdrawn with 12 minutes to go, unclear if due to injury. The only Red Devil in the squad to not see the field was 21-year-old Axel Tuanzebe.