This is far from ideal for a United side already low in confidence after a dreadful start to the season.
De Gea injured his groin while on international duty with Spain on Tuesday as he injured an abductor while kicking a ball against Sweden in a EURO 2020 qualifier. He is expected to have a full assessment in Manchester on Thursday but isn’t expected to be available to play against Liverpool.
As for Pogba, he suffered a reoccurrence of his foot injury before the international break and has been training in Dubai on his own during the past week to try and speed up his recovery.
Ole Gunnar Solskjaer has already been without Pogba, Luke Shaw, Anthony Martial and Aaron Wan-Bissaka for large chunks of the season so far, as Man United sit in 12th place in the Premier League table.
“No chance,” Solskjaer said of Pogba’s availability for the weekend. “Paul had an injury, then came back, worked really hard, played a couple of games. Maybe played through the pain barrier. We had a scan after the Arsenal game and he needed a few weeks rest in the boot. Hopefully he won’t be too long but he won’t make this game, no.”
Not having their star goalkeeper and central midfielder available for this clash with bitter rivals Liverpool is another huge setback for Solskjaer, as Sergio Romero and Fred will likely start in their place.
Martial, Shaw and Wan-Bissaka are all expected to miss the game against Liverpool too as Solskjaer will at least have a valid excuse if the Premier League leaders give United a hiding on Sunday.