Only two matches on Monday involved countries heading to Russia this summer, but each fixture featured exciting action.
The Portuguese fell behind after 11 minutes, when Depay led a brilliant attack for the Dutch. The lead soon doubled just beyond the half-hour mark as Babel’s sliding effort found its way past goalkeeper Anthony Lopes.
Liverpool defender Van Dijk capped off the scoring on the stroke of halftime with a strong strike inside the Portuguese area following a free kick for the Dutch.
The fate of the hosts was sealed in the 61st minute, when defender João Cancelo received his second yellow card in less than 20 minutes, and was sent off.
Meanwhile, Edinson Cavani’s second-half strike helped Uruguay top Wales with a 1-0 victory on the road.
The South American side was outmatched for much of the fixture, with Gareth Bale and Wales looking the more dominant side, but the PSG star found the back of the net four minutes into the second stanza after Cristian Rodríguez picked out the veteran striker — who was positioned close to goal.Follow @MattReedFutbol